Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Good
Based on 192 Reviews
8.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Melatonin
10 mg
**
Top Medical Research Studies
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
Most Useful Reviews
9.5
Effective sleep aid
Good dosage! It’s great for helping you sleep and does its job well. My grandmother suffers from persistent insomnia; she tried taking half a pill, but it wasn't sufficient. A whole pill enables her to fall asleep without problems.
Read More
9.5
Natural sleep aid
It's fantastic; I can't do without it! As life progresses and with age, falling asleep becomes more challenging, but this pill makes it quick and natural, with no dependencies or side effects. It greatly enhances life quality, providing restful sleep and readiness to wake. The sweet taste adds to the experience. For sensitive individuals, starting with lower doses is suggested. If you find my review helpful, please mark it as effective.
Read More
9.5
Great alternative
Fantastic! I used to take Temazepam on and off, but after being lectured by my doctor about sleeping pills, I was relieved to find this alternative. A friend gave me a sample; it worked so well that I sought out a bottle at my local chemist and found it significantly cheaper on iHerb. It works brilliantly!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
- All Researches
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored REM sleep behavior disorder (RBD) as a complex condition that can be linked to a variety of underlying disorders. Through a literature review and insights from foundational texts, we recognized that RBD may emerge at any age and can initially appear as an isolated issue or be associated with other significant conditions like Parkinson’s and narcolepsy.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 192 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Effective sleep aid
Good dosage! It’s great for helping you sleep and does its job well. My grandmother suffers from persistent insomnia; she tried taking half a pill, but it wasn't sufficient. A whole pill enables her to fall asleep without problems.
Read More
9.5
Natural sleep aid
It's fantastic; I can't do without it! As life progresses and with age, falling asleep becomes more challenging, but this pill makes it quick and natural, with no dependencies or side effects. It greatly enhances life quality, providing restful sleep and readiness to wake. The sweet taste adds to the experience. For sensitive individuals, starting with lower doses is suggested. If you find my review helpful, please mark it as effective.
Read More
9.5
Great alternative
Fantastic! I used to take Temazepam on and off, but after being lectured by my doctor about sleeping pills, I was relieved to find this alternative. A friend gave me a sample; it worked so well that I sought out a bottle at my local chemist and found it significantly cheaper on iHerb. It works brilliantly!
Read More
10
Godsend for sleep
This is a godsend for those who sleep poorly. I didn't believe any ordinary supplement could resolve my sleep issues. Just one tablet, taken 30 minutes before bed, makes me drowsy. It dissolves quickly under the tongue, has a pleasant cherry flavour, and I experience vivid dreams. I don't wake up at night, and I rise before my alarm feeling refreshed. Therefore, it's a solid 5 from me; I will certainly continue using it.
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9.5
Effective sleep aid
An excellent product, effectively normalising sleep. I appreciate its dosage compared to the usual 3-5 mg. There are 10 mg available, which is beneficial during periods of severe stress. Taken 30 minutes prior to sleep, it induces restful sleep with no grogginess in the morning. I highly recommend it for those with sleep problems.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Wei Z, Shen H, Wang F, Huang W, Li X, et al. Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients. Ann Med. 2024;56:2361825. doi:10.1080/07853890.2024.2361825
- Motlaq TM, Rahimi B, Amini S. Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial. J Pharm Health Care Sci. 2024;10:25. doi:10.1186/s40780-024-00347-9
- Dastan F, Gholizadeh Niari B, Adimi Naghan P, Barati S, Eskandari R. Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea. J Pharm Pharm Sci. 2023;25:418. doi:10.18433/jpps33252
- Schenck CH. REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications [Commentary]. Sleep Breath. 2022;26:1289. doi:10.1007/s11325-022-02574-6
